Platelet Rich Plasma - Platelet Counts and Application - A Literature Review

Platelet rich plasma (PRP) is a novel method of using plasma concentrated with platelets for wound healing and tissue regeneration. Platelet rich plasma is prepared from the venous blood using a differential centrifugation technique. It involves a separation spin and a concentration spin, yielding platelet rich plasma. PRP products have been classified into 4 types depending upon major cell constituent and fibrin density upon activation. These are as follows: Pure PRP, Leukocyte and PRP, Pure PRF, Leukocyte and PRF. PRF differs from PRP in that it is rich in a high density fibrin network after activation. PRP is abundant in a variety of growth factors such as VEGF, PDGF, TGF, EGF, and Interleukin-1. Literature consists of reports by different authors about the platelet yield of PRP centrifuged by different systems. A number of factors have also been quoted to influence the platelet concentration in platelet rich plasma. Hence, the aim of this review is to discuss the platelet concentration in PRP centrifuged by different systems and to observe for variations if any

Death due to airgun injury: a case report.

In medicolegal practice, the examination of injuries is very important to solve the medicolegal problems like weapon identification, age of the injury, fatality, ante mortem or postmortem etc. Commonly the firearms are classified like rifled guns and smooth bored guns. Usually cases encountered are from these weapons. In these weapons gun powder is used to propel the projectile. The preliminary knowledge of these weapons is important to identify the weapon. In case of airgun, compressed air is used to propel the projectile. An airgun is a rifle, pistol or shotgun which fires projectiles by means of compressed air or gas in contrast to a firearm which burns a propellant. Most airguns use metallic projectiles called as pellets. The death due airgun is rare. The death that happened in this case is discussed in detail due to rarity of its kind. During the injury examination, the analysis of the injury is important. Its size, shape, nature of margins, abrasions coller, grease coller, tattooing, soot, and burns are all to be noted in firearm injuries to decide the weapon, entry or exit wound etc.

EMM types of streptococcus pyogenes in Chennai.

The M protein of group A Streptococcus (GAS) is the major virulence factor and is coded by the emm gene. The current serologic M typing methods are now being replaced by alternate means of M type deduction such as emm gene sequencing. This is the first report of emm types of GAS which are prevalent in south India. We found no marked preponderance of any single emm sequence among our clinical isolates with 11 emm sequences being present in 34 isolates.